HitPredict

Interactor 1: MYCL (P12524)
Protein L-Myc (Class E basic helix-loop-helix protein 38) (bHLHe38) (Protein L-Myc-1) (V-myc myelocytomatosis viral oncogene homolog)
Gene: MYCL

Interactor 2: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 364 Hs			1 1235
+	Hs
		347855 MYC_HUMAN (1-362): 1e-76: 245: 29.75		BRD8_HUMAN (1-1235): 0: 594: 100.00
+	Hs
		346644 MYC_HUMAN (1-362): 1e-76: 245: 29.75		BPTF_HUMAN (130-1222): 5.45e-42: 171: 9.55
+	Hs
		347493 MYC_HUMAN (1-362): 1e-76: 245: 29.75		KAT2B_HUMAN (1075-1209): 2.89e-37: 154: 23.70
+	Hs
		348246 MYC_HUMAN (1-362): 1e-76: 245: 29.75		TRI33_HUMAN (820-1232): 7.65e-33: 140: 11.56
+	Hs
		170198 MYC_HUMAN (1-362): 1e-76: 245: 29.75		TIF1A_HUMAN (845-1228): 4.33e-31: 134: 14.07
+	Mm
		348442 MYC_MOUSE (1-362): 4.56e-78: 248: 29.98		BRD8_MOUSE (850-1235): 3.98e-30: 131: 29.24
+	Hs
		348175 MYC_HUMAN (1-362): 1e-76: 245: 29.75		BAZ2A_HUMAN (125-815): 2.72e-30: 132: 10.85
+	Hs
		347970 MYC_HUMAN (1-362): 1e-76: 245: 29.75		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		346630 MYC_HUMAN (1-362): 1e-76: 245: 29.75		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		379678 MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05		KAT2B_HUMAN (1075-1209): 2.89e-37: 154: 23.70
+	Hs
		347201 MYC_HUMAN (1-362): 1e-76: 245: 29.75		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		345919 MYC_HUMAN (1-362): 1e-76: 245: 29.75		TAF1_HUMAN (1002-1220): 5.29e-22: 105: 15.32
+	Hs
		346268 MYC_HUMAN (1-362): 1e-76: 245: 29.75		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Hs
		379904 MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		379333 MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		347443 MYC_HUMAN (1-362): 1e-76: 245: 29.75		PHIP_HUMAN (1059-1206): 1.19e-14: 81.5: 15.23
+	Hs
		347492 MYC_HUMAN (1-362): 1e-76: 245: 29.75		KAT2A_HUMAN (684-810): 1.1e-12: 74.9: 17.32
+	Hs
		347489 MYC_HUMAN (1-362): 1e-76: 245: 29.75		CBP_HUMAN (125-595): 9.03e-09: 62.2: 12.22
+	Hs
		379142 MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Hs
		998758 USF2_HUMAN (46-362): 1.87e-51: 176: 19.76		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66