HitPredict

Interactor 1: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Interactor 2: RN149 (Q8NC42)
E3 ubiquitin-protein ligase RNF149 (EC 2.3.2.27) (DNA polymerase-transactivated protein 2) (RING finger protein 149) (RING-type E3 ubiquitin transferase RNF149)
Gene: RNF149

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	33961781, 36610398
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1907 Hs			1 400
+	Hs
		1102728 PTPRS_HUMAN (1-1907): 0: 1569: 65.52		RN149_HUMAN (1-400): 1.38e-131: 385: 100.00
+	Hs
		522708 PTPRF_HUMAN (1-1907): 0: 1645: 100.00		RN133_HUMAN (3-371): 3.01e-98: 299: 30.87
+	Hs
		522704 PTPRF_HUMAN (1-1907): 0: 1645: 100.00		RN128_HUMAN (7-387): 1.02e-93: 289: 37.98
+	Hs
		658915 PTPRD_HUMAN (29-1907): 0: 1562: 69.67		RN133_HUMAN (3-371): 3.01e-98: 299: 30.87
+	Hs
		614710 PTPRA_HUMAN (1138-1907): 0: 808: 40.08		RN149_HUMAN (1-400): 1.38e-131: 385: 100.00
+	Hs
		614744 PTPRA_HUMAN (1138-1907): 0: 808: 40.08		AMFR_HUMAN (96-398): 1.27e-38: 148: 15.29
+	Hs
		1359341 PTPRU_HUMAN (202-746): 3.05e-20: 100: 14.36		ZNRF4_HUMAN (32-389): 2.91e-55: 189: 18.35
+	Hs
		705733 PTPRM_HUMAN (105-534): 3.34e-12: 74.3: 14.22		AMFR_HUMAN (96-398): 1.27e-38: 148: 15.29