HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: PCBP1 (Q15365)
Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1) (Nucleic acid-binding protein SUB2.3)
Gene: PCBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27684187, 35102251
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 356
+	Hs
		525008 XRCC5_HUMAN (1-732): 0: 755: 100.00		FUBP1_HUMAN (224-352): 2.53e-13: 72.9: 22.48
+	Hs
		523778 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00
+	Hs
		128009 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		IF2B3_HUMAN (1-187): 4.45e-25: 107: 25.13
+	Hs
		523922 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		FUBP1_HUMAN (224-352): 2.53e-13: 72.9: 22.48
+	Hs
		523917 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		FUBP2_HUMAN (237-352): 3.22e-13: 72.5: 26.72