HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: PPP5 (Q60676)
Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PPT)
Gene: Ppp5c

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008017 - microtubule binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 733 Mm			1 499
+	Hs
		529399 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PPP5_HUMAN (1-499): 0: 571: 97.80
+	Mm
		530779 TAU_MOUSE (1-733): 2.37e-87: 292: 100.00		PP2AA_MOUSE (190-481): 1.99e-165: 471: 40.20
+	Mm
		530752 TAU_MOUSE (1-733): 2.37e-87: 292: 100.00		PP1A_MOUSE (196-479): 1.16e-155: 447: 37.90
+	Mm
		530773 TAU_MOUSE (1-733): 2.37e-87: 292: 100.00		PP1G_MOUSE (196-488): 6.52e-156: 447: 36.55
+	Mm
		631787 MTAP2_MOUSE (3-733): 2.71e-33: 140: 27.05		PPP5_MOUSE (1-499): 0: 570: 100.00
+	Hs
		529587 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PP2AA_HUMAN (190-481): 1.41e-165: 472: 40.20
+	Hs
		529536 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PP2AB_HUMAN (182-485): 4.76e-162: 462: 38.36
+	Hs
		529508 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PP1B_HUMAN (196-490): 1.34e-157: 452: 34.95
+	Hs
		529234 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PP1G_HUMAN (196-488): 9.24e-156: 447: 36.55
+	Hs
		529507 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PP1A_HUMAN (196-479): 2.9e-155: 446: 37.90
+	Mm
		92770 D3Z656_MOUSE (242-636): 8.7e-10: 64.7: 10.35		PPP5_MOUSE (1-499): 0: 570: 100.00
+	Dm
		1475710 Q9VPR2_DROME (1-627): 6.07e-20: 97: 9.62		Q9VH81_DROME (3-494): 1.06e-179: 516: 60.04
+	Bt
		709190 TAU_BOVIN (315-733): 1.37e-34: 139: 63.01		PP2AA_BOVIN (190-481): 1.41e-165: 472: 40.20
+	Dm
		55696 A1Z9J3_DROME (102-697): 9.51e-28: 123: 11.70		Q8T0U6_DROME (144-479): 1.2e-162: 470: 33.63
+	Hs
		698257 MAP4_HUMAN (26-726): 1.81e-32: 137: 21.70		PP1A_HUMAN (196-479): 2.9e-155: 446: 37.90
+	Hs
		967671 ANK2_HUMAN (120-695): 2.29e-25: 115: 17.02		PP1A_HUMAN (196-479): 2.9e-155: 446: 37.90
+	Hs
		994221 MDC1_HUMAN (25-730): 2.08e-16: 86.2: 8.73		PP2AA_HUMAN (190-481): 1.41e-165: 472: 40.20
+	Hs
		967727 MDC1_HUMAN (25-730): 2.08e-16: 86.2: 8.73		PP1A_HUMAN (196-479): 2.9e-155: 446: 37.90
+	Mm
		693421 MAP4_MOUSE (26-724): 5.88e-10: 65: 10.95		PP1A_MOUSE (196-479): 1.16e-155: 447: 37.90
+	Dm
		119664 M9PB30_DROME (3-402): 7.15e-10: 65.1: 8.00		PP1B_DROME (193-481): 2.04e-152: 439: 36.90