HitPredict

Interactor 1: RAD18 (P10862)
Postreplication repair E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAD18) (Radiation sensitivity protein 18)
Gene: RAD18

Interactor 2: UBC9 (P50623)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)
Gene: UBC9

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.863

Property	Details
Experiments	23034805, 24224485, 12226657
Identification Methods	pull down, two hybrid, enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 487 Sc			1 157
+	Hs
		623204 RO52_HUMAN (15-392): 4.02e-95: 297: 12.59		UB2D1_HUMAN (4-156): 1.2e-74: 221: 33.99
+	Hs
		623249 RO52_HUMAN (15-392): 4.02e-95: 297: 12.59		UB2D2_HUMAN (4-156): 2.56e-74: 220: 32.68
+	Hs
		623219 RO52_HUMAN (15-392): 4.02e-95: 297: 12.59		UB2D3_HUMAN (4-156): 3.19e-73: 217: 32.68
+	Hs
		623264 RO52_HUMAN (15-392): 4.02e-95: 297: 12.59		UBC9_HUMAN (1-156): 1.26e-69: 208: 56.41
+	Hs
		623207 RO52_HUMAN (15-392): 4.02e-95: 297: 12.59		UB2E1_HUMAN (3-156): 2.88e-67: 204: 31.82
+	Hs
		1439327 TRI39_HUMAN (19-414): 1.15e-82: 266: 10.04		UB2D4_HUMAN (4-156): 2.18e-75: 223: 33.33
+	Hs
		906790 TRI39_HUMAN (19-414): 1.15e-82: 266: 10.04		UB2D1_HUMAN (4-156): 1.2e-74: 221: 33.99
+	Hs
		982330 TRI39_HUMAN (19-414): 1.15e-82: 266: 10.04		UB2D2_HUMAN (4-156): 2.56e-74: 220: 32.68
+	Hs
		957102 TRI68_HUMAN (15-392): 9.3e-84: 268: 11.92		UB2D3_HUMAN (4-156): 3.19e-73: 217: 32.68
+	Hs
		957208 TRI39_HUMAN (19-414): 1.15e-82: 266: 10.04		UB2D3_HUMAN (4-156): 3.19e-73: 217: 32.68
+	Hs
		1397295 TRI39_HUMAN (19-414): 1.15e-82: 266: 10.04		UB2E2_HUMAN (3-156): 2.99e-69: 209: 31.17
+	Hs
		957138 TRI58_HUMAN (16-420): 6.36e-80: 258: 12.58		UB2D3_HUMAN (4-156): 3.19e-73: 217: 32.68
+	Hs
		1381205 TRI39_HUMAN (19-414): 1.15e-82: 266: 10.04		UB2E3_HUMAN (3-156): 6.7e-69: 208: 31.17
+	Hs
		571903 TRI27_HUMAN (15-400): 2.08e-77: 253: 8.91		UB2D1_HUMAN (4-156): 1.2e-74: 221: 33.99
+	Hs
		571922 TRI27_HUMAN (15-400): 2.08e-77: 253: 8.91		UB2D2_HUMAN (4-156): 2.56e-74: 220: 32.68
+	Hs
		571915 TRI27_HUMAN (15-400): 2.08e-77: 253: 8.91		UB2D3_HUMAN (4-156): 3.19e-73: 217: 32.68
+	Hs
		909393 TRI39_HUMAN (19-414): 1.15e-82: 266: 10.04		UB2E1_HUMAN (3-156): 2.88e-67: 204: 31.82
+	Hs
		623403 RO52_HUMAN (15-392): 4.02e-95: 297: 12.59		Q7KZS0_HUMAN (1-134): 6.69e-54: 170: 59.70
+	Hs
		571906 TRI27_HUMAN (15-400): 2.08e-77: 253: 8.91		UB2E1_HUMAN (3-156): 2.88e-67: 204: 31.82
+	Hs
		571900 TRI27_HUMAN (15-400): 2.08e-77: 253: 8.91		UBE2A_HUMAN (1-154): 2.59e-67: 203: 38.96