HitPredict

Interactor 1: POXN (P23758)
Paired box pox-neuro protein (Paired box neuronal protein)
Gene: POXN

Interactor 2: Q7KS72 (Q7KS72)
C15 (FI01111p)
Gene: C15

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	30995488
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0007480 - imaginal disc-derived leg morphogenesis and 1 others more... GO:0048800 - antennal morphogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 425 Dm			1 339
+	Dm
		620099 POXN_DROME (1-402): 0: 526: 100.00		Q058W3_DROME (216-281): 2.37e-13: 72.4: 48.49
+	Hs
		641345 PAX6_HUMAN (3-191): 2.28e-77: 248: 47.64		MNX1_HUMAN (145-314): 1.27e-39: 146: 28.50
+	Dm
		588486 Q59DN8_DROME (1-183): 6.24e-75: 250: 51.91		DLL_DROME (151-335): 2.43e-36: 135: 23.98
+	Dm
		183625 O16117_DROME (1-183): 7.59e-74: 248: 51.91		DLL_DROME (151-335): 2.43e-36: 135: 23.98
+	Hs
		837763 PAX8_HUMAN (1-174): 3.51e-72: 235: 54.65		MNX1_HUMAN (145-314): 1.27e-39: 146: 28.50
+	Hs
		837762 PAX9_HUMAN (3-197): 3.56e-73: 234: 49.75		MNX1_HUMAN (145-314): 1.27e-39: 146: 28.50
+	Hs
		238108 PAX2_HUMAN (3-197): 1.95e-79: 253: 52.31		LMX1B_HUMAN (174-338): 1.02e-31: 124: 17.75
+	Hs
		641327 PAX6_HUMAN (3-191): 2.28e-77: 248: 47.64		HXC8_HUMAN (123-285): 7.88e-35: 129: 22.75
+	Hs
		678900 PAX5_HUMAN (2-361): 4.38e-78: 248: 36.26		HXC8_HUMAN (123-285): 7.88e-35: 129: 22.75
+	Hs
		620134 PAX7_HUMAN (5-158): 1.5e-69: 230: 55.77		MNX1_HUMAN (145-314): 1.27e-39: 146: 28.50
+	Dm
		185797 PAX6_DROME (3-234): 2.84e-71: 242: 39.68		ANTP_DROME (155-286): 2.41e-34: 131: 27.74
+	Hs
		799089 PAX8_HUMAN (1-174): 3.51e-72: 235: 54.65		NKX21_HUMAN (69-279): 7.25e-36: 135: 23.79
+	Mm
		837774 PAX8_MOUSE (1-174): 8.59e-72: 234: 54.65		NKX21_MOUSE (69-312): 1.54e-35: 134: 20.77
+	Rn
		616671 PAX8_RAT (1-174): 3.32e-71: 233: 54.65		NKX21_RAT (69-312): 1.01e-35: 134: 20.77
+	Hs
		678904 PAX8_HUMAN (1-174): 3.51e-72: 235: 54.65		HXC8_HUMAN (123-285): 7.88e-35: 129: 22.75
+	Mm
		192281 PAX3_MOUSE (5-185): 9.31e-75: 242: 50.83		ALX4_MOUSE (123-337): 1.42e-30: 121: 21.10
+	Hs
		973860 PAX2_HUMAN (3-197): 1.95e-79: 253: 52.31		ZFHX4_HUMAN (164-303): 3.96e-11: 66.6: 15.00
+	Hs
		641468 PAX6_HUMAN (3-191): 2.28e-77: 248: 47.64		ZFHX4_HUMAN (164-303): 3.96e-11: 66.6: 15.00
+	Hs
		988779 PAX8_HUMAN (1-174): 3.51e-72: 235: 54.65		ZFHX4_HUMAN (164-303): 3.96e-11: 66.6: 15.00
+	Hs
		878430 PAX9_HUMAN (3-197): 3.56e-73: 234: 49.75		ZFHX4_HUMAN (164-303): 3.96e-11: 66.6: 15.00