Interactor 1: BRAF (P15056)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)
Gene: BRAF
Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 27034005, 27684187, 31980649, 33961781, 32707033, 17979178, 35271311, 36931259, unassigned2173 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation, pull down, cross-linking study |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 14-3-3~C1_1, 14-3-3~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0000165 - MAPK cascade GO:0005634 - nucleus GO:0005829 - cytosol GO:0097110 - scaffold protein binding |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
