HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: MCR1 (P36060)
NADH-cytochrome b5 reductase 2 (EC 1.6.2.2) (Mitochondrial cytochrome b reductase) (p34/p32) [Cleaved into: NADH-cytochrome b5 reductase p34 form; NADH-cytochrome b5 reductase p32 form]
Gene: MCR1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35876647, 37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 302
+	Sc
		366113 HSP82_YEAST (1-705): 0: 968: 95.63		MCR1_YEAST (1-302): 9.84e-103: 304: 100.00
+	Hs
		437940 HS90B_HUMAN (5-705): 0: 1022: 61.15		NOS2_HUMAN (17-300): 1.26e-69: 235: 13.10
+	Hs
		431564 HS90A_HUMAN (4-705): 0: 1013: 60.67		NOS3_HUMAN (17-300): 1.26e-70: 238: 18.30
+	Hs
		431587 HS90A_HUMAN (4-705): 0: 1013: 60.67		NOS2_HUMAN (17-300): 1.26e-69: 235: 13.10
+	Ss
		137796 HS90A_PIG (4-705): 0: 1012: 60.45		NOS3_PIG (17-300): 4.9e-68: 231: 17.67
+	Sc
		543662 HSC82_YEAST (1-705): 0: 977: 100.00		NCB5R_YEAST (37-302): 7.16e-79: 243: 30.37
+	Sc
		544660 HSC82_YEAST (1-705): 0: 977: 100.00		PGA3_YEAST (28-302): 4.69e-77: 239: 31.64
+	Sc
		366219 HSP82_YEAST (1-705): 0: 968: 95.63		NCB5R_YEAST (37-302): 7.16e-79: 243: 30.37
+	Sc
		367149 HSP82_YEAST (1-705): 0: 968: 95.63		PGA3_YEAST (28-302): 4.69e-77: 239: 31.64
+	Sc
		543762 HSC82_YEAST (1-705): 0: 977: 100.00		FHP_YEAST (48-300): 1.43e-46: 162: 16.54
+	Sc
		366314 HSP82_YEAST (1-705): 0: 968: 95.63		FHP_YEAST (48-300): 1.43e-46: 162: 16.54