HitPredict

Interactor 1: PVR (P15151)
Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155)
Gene: PVR

Interactor 2: RAB5B (P61020)
Ras-related protein Rab-5B (EC 3.6.5.2)
Gene: RAB5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 417 Hs			1 215
+	Hs
		592415 NECT2_HUMAN (25-333): 4.43e-71: 234: 52.80		RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86
+	Hs
		844662 NECT2_HUMAN (25-333): 4.43e-71: 234: 52.80		RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26
+	Hs
		914262 NECT2_HUMAN (25-333): 4.43e-71: 234: 52.80		RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61
+	Hs
		914381 NECT3_HUMAN (26-389): 5.45e-69: 229: 24.20		RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61
+	Hs
		592622 ROBO1_HUMAN (19-407): 1.02e-47: 177: 15.50		RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86
+	Hs
		914506 ROBO1_HUMAN (19-407): 1.02e-47: 177: 15.50		RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61
+	Hs
		592436 KIRR1_HUMAN (238-415): 4.33e-10: 63.8: 7.73		RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86
+	Hs
		844686 KIRR1_HUMAN (238-415): 4.33e-10: 63.8: 7.73		RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26
+	Hs
		914281 KIRR1_HUMAN (238-415): 4.33e-10: 63.8: 7.73		RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61
+	Hs
		914253 TITIN_HUMAN (178-333): 3.86e-09: 61.2: 11.25		RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61