HitPredict

Interactor 1: VATB1 (P15313)
V-type proton ATPase subunit B, kidney isoform (V-ATPase subunit B 1) (Endomembrane proton pump 58 kDa subunit) (Vacuolar proton pump subunit B 1)
Gene: ATP6V1B1

Interactor 2: WDR7 (Q9Y4E6)
WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)
Gene: WDR7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 1490
+	Mm
		1265222 VATB1_MOUSE (1-513): 0: 646: 93.76		WDR7_MOUSE (1-1490): 0: 1503: 93.31
+	Hs
		597714 VATB2_HUMAN (21-503): 0: 594: 88.61		WDR7_HUMAN (1-1490): 0: 1534: 98.26
+	Dm
		680254 VATB_DROME (21-502): 0: 597: 86.54		Q9W543_DROME (1-1490): 0: 1092: 39.09
+	Sc
		556304 VATB_YEAST (17-498): 0: 581: 76.97		UTP13_YEAST (8-287): 9.58e-24: 111: 13.70
+	Sc
		555988 VATB_YEAST (17-498): 0: 581: 76.97		TAF5_YEAST (22-346): 6.89e-15: 82.2: 14.62
+	Sc
		556388 VATB_YEAST (17-498): 0: 581: 76.97		PRP46_YEAST (55-402): 7.01e-12: 71.4: 13.47
+	Hs
		415288 ATPB_HUMAN (41-497): 1.42e-158: 463: 23.23		WDR5_HUMAN (16-237): 2.88e-33: 134: 13.90
+	Sc
		342114 ATPB_YEAST (41-505): 3.19e-160: 466: 22.45		UTP13_YEAST (8-287): 9.58e-24: 111: 13.70
+	Hs
		415535 ATPB_HUMAN (41-497): 1.42e-158: 463: 23.23		FBW1B_HUMAN (281-588): 8.72e-20: 97.2: 15.97
+	Hs
		415544 ATPB_HUMAN (41-497): 1.42e-158: 463: 23.23		FBW1A_HUMAN (433-763): 4.04e-13: 76: 10.39
+	Sc
		342147 ATPB_YEAST (41-505): 3.19e-160: 466: 22.45		PRP46_YEAST (55-402): 7.01e-12: 71.4: 13.47