Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1
Interactor 2: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.979 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8074697, 27684187, 14517306, 22375065, 25468996, 7542250, 9535896, 8207061, 1639850, 34591612, 9700170, 11801604, 17524503 |
| Identification Methods | pull down, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Arm~CADH_Y-type_LIR |
| Common GO terms | GO:0002159 - desmosome assembly GO:0005576 - extracellular region GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005912 - adherens junction and 11 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
