HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: SEM3F (Q13275)
Semaphorin-3F (Sema III/F) (Semaphorin IV) (Sema IV)
Gene: SEMA3F

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030335 - positive regulation of cell migration
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1089 Hs			1 785
+	Hs
		303596 PGFRA_HUMAN (1-1089): 0: 817: 100.00		SEM3D_HUMAN (6-781): 0: 843: 44.12
+	Hs
		557235 PGFRA_HUMAN (1-1089): 0: 817: 100.00		SEM3C_HUMAN (11-785): 0: 800: 50.71
+	Hs
		557111 PGFRA_HUMAN (1-1089): 0: 817: 100.00		SEM3B_HUMAN (2-784): 0: 756: 46.76
+	Hs
		557260 PGFRA_HUMAN (1-1089): 0: 817: 100.00		SEM4B_HUMAN (30-723): 0: 600: 28.81
+	Hs
		557265 PGFRA_HUMAN (1-1089): 0: 817: 100.00		SEM4G_HUMAN (7-696): 0: 579: 30.13
+	Hs
		557252 PGFRA_HUMAN (1-1089): 0: 817: 100.00		SEM6B_HUMAN (14-670): 5.63e-166: 504: 25.59
+	Hs
		609568 FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74		SEM4G_HUMAN (7-696): 0: 579: 30.13
+	Dm
		1097362 PTK7_DROME (131-637): 1.77e-26: 119: 13.24		SEM1A_DROME (8-678): 4.2e-166: 505: 25.32