HitPredict

Interactor 1: GP1BB (P13224)
Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (Antigen CD42b-beta) (CD antigen CD42c)
Gene: GP1BB

Interactor 2: CL12B (Q2HXU8)
C-type lectin domain family 12 member B (Macrophage antigen H)
Gene: CLEC12B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 206 Hs			1 276
+	Hs
		1177804 LRC24_HUMAN (10-91): 4.94e-16: 77.7: 24.39		CL12B_HUMAN (1-276): 4.18e-82: 249: 100.00
+	Hs
		1177819 R4RL2_HUMAN (10-134): 3e-14: 72.3: 21.43		CL12B_HUMAN (1-276): 4.18e-82: 249: 100.00
+	Hs
		320874 LRIG2_HUMAN (7-89): 4.44e-11: 63.4: 19.05		CL12B_HUMAN (1-276): 4.18e-82: 249: 100.00
+	Hs
		1177813 LRIG3_HUMAN (4-89): 7.8e-11: 62.7: 20.69		CL12B_HUMAN (1-276): 4.18e-82: 249: 100.00
+	Hs
		1177865 LRIG1_HUMAN (2-89): 1.88e-09: 58.4: 12.59		CL12B_HUMAN (1-276): 4.18e-82: 249: 100.00
+	Hs
		1310185 AGRA3_HUMAN (3-197): 1.4e-44: 160: 16.84		CLC2B_HUMAN (130-266): 8.32e-41: 139: 32.12
+	Hs
		561001 GP1BB_HUMAN (1-206): 2.89e-44: 148: 100.00		CLC2D_HUMAN (143-266): 1.26e-35: 128: 29.03
+	Hs
		317580 SLIT2_HUMAN (2-196): 1.03e-32: 125: 18.97		CLC4D_HUMAN (119-264): 1.29e-39: 139: 24.52
+	Hs
		1334433 LRC4C_HUMAN (18-92): 2.37e-09: 58: 14.67		CLC1A_HUMAN (3-275): 5.88e-51: 170: 32.48
+	Hs
		1249715 LRC4C_HUMAN (18-92): 2.37e-09: 58: 14.67		CLC4G_HUMAN (58-269): 8.59e-47: 159: 23.39
+	Hs
		320910 LRIG2_HUMAN (7-89): 4.44e-11: 63.4: 19.05		CLC4E_HUMAN (132-265): 1.44e-40: 141: 31.21
+	Hs
		320883 LRIG2_HUMAN (7-89): 4.44e-11: 63.4: 19.05		CLC4D_HUMAN (119-264): 1.29e-39: 139: 24.52
+	Hs
		1360914 LRIG1_HUMAN (2-89): 1.88e-09: 58.4: 12.59		CLC4D_HUMAN (119-264): 1.29e-39: 139: 24.52
+	Hs
		688615 LRIG1_HUMAN (2-89): 1.88e-09: 58.4: 12.59		NKG2A_HUMAN (3-267): 2.07e-35: 128: 22.47