HitPredict

Interactor 1: AT2A2 (P16615)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1042 Hs			1 768
+	Hs
		163802 AT2A1_HUMAN (1-1000): 0: 961: 83.72		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		393192 AT1A1_HUMAN (3-997): 0: 797: 26.72		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041527 AT1A4_HUMAN (3-997): 0: 790: 27.85		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		843458 AT1A2_HUMAN (3-997): 0: 788: 26.45		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		393193 AT1A1_HUMAN (3-997): 0: 797: 26.72		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		393194 AT1A1_HUMAN (3-997): 0: 797: 26.72		CUL4B_HUMAN (5-768): 0: 779: 36.77