HitPredict

Interactor 1: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	37120454, 18566587
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001938 - positive regulation of endothelial cell proliferation GO:0005829 - cytosol GO:0018105 - peptidyl-serine phosphorylation
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 672 Hs			1 1708
+	Hs
		408632 KPCB_HUMAN (1-664): 0: 749: 78.89		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		681904 AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		117012 SGK1_HUMAN (255-661): 1.16e-153: 452: 38.85		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		983861 KPCZ_HUMAN (22-98): 3.2e-11: 68.6: 34.44		RICTR_HUMAN (1-1708): 0: 2775: 100.00