HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: RON (Q04912)
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
Gene: MST1R

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0009986 - cell surface
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 645 Hs			1 1400
+	Hs
		471972 PDIA4_HUMAN (1-645): 0: 564: 100.00		MET_HUMAN (1-1391): 0: 1071: 32.30
+	Hs
		452239 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		RON_HUMAN (19-1400): 0: 1279: 100.00
+	Mm
		107235 TXND5_MOUSE (417-643): 1.73e-40: 154: 19.57		F8VQL0_MOUSE (1-1364): 0: 1078: 33.36
+	Hs
		566564 PDIA4_HUMAN (1-645): 0: 564: 100.00		EPHB2_HUMAN (557-1369): 1.17e-165: 527: 16.63
+	Hs
		566563 PDIA4_HUMAN (1-645): 0: 564: 100.00		EPHA8_HUMAN (643-1350): 1.15e-155: 498: 19.65
+	Hs
		541304 PDIA4_HUMAN (1-645): 0: 564: 100.00		FGFR1_HUMAN (767-1397): 1.17e-113: 379: 22.74
+	Hs
		566653 PDIA4_HUMAN (1-645): 0: 564: 100.00		MERTK_HUMAN (1037-1348): 1.21e-59: 225: 37.65
+	Hs
		566645 PDIA4_HUMAN (1-645): 0: 564: 100.00		TYRO3_HUMAN (1062-1348): 1.01e-59: 224: 41.95
+	Hs
		566576 PDIA4_HUMAN (1-645): 0: 564: 100.00		RYK_HUMAN (1050-1348): 3.59e-61: 223: 39.42
+	Hs
		566572 PDIA4_HUMAN (1-645): 0: 564: 100.00		UFO_HUMAN (1062-1348): 3.98e-56: 213: 40.47
+	Hs
		465390 PDIA4_HUMAN (1-645): 0: 564: 100.00		IGF1R_HUMAN (1072-1343): 3.58e-52: 204: 37.93
+	Hs
		439629 PDIA4_HUMAN (1-645): 0: 564: 100.00		INSR_HUMAN (1073-1338): 8.51e-51: 199: 38.73
+	Hs
		710081 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		EPHA2_HUMAN (557-1375): 4.82e-160: 509: 16.67
+	Hs
		452140 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		FGFR1_HUMAN (767-1397): 1.17e-113: 379: 22.74
+	Hs
		720273 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		UFO_HUMAN (1062-1348): 3.98e-56: 213: 40.47
+	Hs
		465572 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		IGF1R_HUMAN (1072-1343): 3.58e-52: 204: 37.93
+	Hs
		439778 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		INSR_HUMAN (1073-1338): 8.51e-51: 199: 38.73
+	Hs
		452177 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		UFO_HUMAN (1062-1348): 3.98e-56: 213: 40.47
+	Hs
		452130 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		IGF1R_HUMAN (1072-1343): 3.58e-52: 204: 37.93
+	Hs
		439615 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		INSR_HUMAN (1073-1338): 8.51e-51: 199: 38.73