HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: EPHAA (Q5JZY3)
Ephrin type-A receptor 10 (EC 2.7.10.1)
Gene: EPHA10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 645 Hs			1 1008
+	Hs
		566564 PDIA4_HUMAN (1-645): 0: 564: 100.00		EPHB2_HUMAN (35-1008): 0: 1118: 41.85
+	Hs
		566563 PDIA4_HUMAN (1-645): 0: 564: 100.00		EPHA8_HUMAN (6-1004): 0: 1052: 43.68
+	Hs
		181773 PDIA4_HUMAN (1-645): 0: 564: 100.00		EPHB6_HUMAN (18-991): 0: 895: 37.12
+	Hs
		1207821 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		EPHAA_HUMAN (1-1008): 0: 1117: 100.00
+	Hs
		452281 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		EPHAA_HUMAN (1-1008): 0: 1117: 100.00
+	Hs
		717499 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		EPHAA_HUMAN (1-1008): 0: 1117: 100.00
+	Hs
		710081 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		EPHA2_HUMAN (33-1008): 0: 1011: 40.67
+	Hs
		566572 PDIA4_HUMAN (1-645): 0: 564: 100.00		UFO_HUMAN (292-985): 1.49e-155: 484: 21.60
+	Hs
		439629 PDIA4_HUMAN (1-645): 0: 564: 100.00		INSR_HUMAN (290-962): 6.07e-140: 455: 22.98
+	Hs
		566645 PDIA4_HUMAN (1-645): 0: 564: 100.00		TYRO3_HUMAN (300-904): 4.22e-143: 451: 23.14
+	Hs
		566653 PDIA4_HUMAN (1-645): 0: 564: 100.00		MERTK_HUMAN (303-927): 6.01e-141: 449: 19.97
+	Hs
		720273 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		UFO_HUMAN (292-985): 1.49e-155: 484: 21.60
+	Hs
		572942 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		INSRR_HUMAN (296-941): 4.18e-141: 457: 23.60
+	Hs
		439778 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		INSR_HUMAN (290-962): 6.07e-140: 455: 22.98
+	Hs
		452177 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		UFO_HUMAN (292-985): 1.49e-155: 484: 21.60
+	Hs
		717373 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		UFO_HUMAN (292-985): 1.49e-155: 484: 21.60
+	Hs
		720276 TXND5_HUMAN (176-391): 3.68e-29: 122: 22.18		UFO_HUMAN (292-985): 1.49e-155: 484: 21.60
+	Hs
		439615 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		INSR_HUMAN (290-962): 6.07e-140: 455: 22.98
+	Hs
		572945 TXND5_HUMAN (176-391): 3.68e-29: 122: 22.18		INSRR_HUMAN (296-941): 4.18e-141: 457: 23.60
+	Hs
		439791 TXND5_HUMAN (176-391): 3.68e-29: 122: 22.18		INSR_HUMAN (290-962): 6.07e-140: 455: 22.98