HitPredict

Interactor 1: P4HA1 (P13674)
Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)
Gene: P4HA1

Interactor 2: EDA (Q92838)
Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Cleaved into: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form]
Gene: EDA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 534 Hs			1 391
+	Hs
		191286 P4HA2_HUMAN (1-534): 0: 695: 61.61		CO6A2_HUMAN (3-193): 3.72e-28: 118: 12.39
+	Hs
		566968 P4HA1_HUMAN (1-534): 0: 716: 100.00		COEA1_HUMAN (7-139): 1.9e-13: 74.2: 11.33
+	Hs
		471578 P4HA1_HUMAN (1-534): 0: 716: 100.00		CO4A2_HUMAN (5-300): 8.32e-12: 69.2: 15.51
+	Hs
		384238 P4HA1_HUMAN (1-534): 0: 716: 100.00		CO2A1_HUMAN (3-199): 1.37e-09: 62.2: 15.75
+	Hs
		566977 P4HA1_HUMAN (1-534): 0: 716: 100.00		CO4A6_HUMAN (1-178): 5.96e-09: 60.3: 7.78
+	Hs
		191318 P4HA2_HUMAN (1-534): 0: 695: 61.61		COEA1_HUMAN (7-139): 1.9e-13: 74.2: 11.33
+	Hs
		191281 P4HA2_HUMAN (1-534): 0: 695: 61.61		CO4A2_HUMAN (5-300): 8.32e-12: 69.2: 15.51
+	Hs
		191285 P4HA2_HUMAN (1-534): 0: 695: 61.61		CO6A1_HUMAN (5-135): 1.06e-11: 68.7: 12.58
+	Hs
		191284 P4HA2_HUMAN (1-534): 0: 695: 61.61		COBA1_HUMAN (24-273): 1.1e-10: 65.7: 19.78
+	Hs
		191279 P4HA2_HUMAN (1-534): 0: 695: 61.61		CO5A2_HUMAN (1-143): 3.97e-10: 63.7: 9.79
+	Hs
		191292 P4HA2_HUMAN (1-534): 0: 695: 61.61		CO5A1_HUMAN (7-272): 6.04e-09: 60.3: 14.70
+	Hs
		191371 P4HA2_HUMAN (1-534): 0: 695: 61.61		COMA1_HUMAN (69-247): 6.15e-09: 60.1: 21.31
+	Hs
		1251856 P4HA3_HUMAN (17-534): 0: 536: 36.31		SCAR5_HUMAN (149-260): 1.1e-18: 89.4: 28.91