HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: FRAS1 (Q86XX4)
Extracellular matrix organizing protein FRAS1 (Fraser syndrome 1 protein)
Gene: FRAS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 4008
+	Hs
		1294398 PRG3_HUMAN (12-222): 1.53e-53: 173: 49.30		FRAS1_HUMAN (1-4008): 0: 2793: 100.00
+	Mm
		1228174 FREM1_MOUSE (31-221): 6.48e-35: 132: 17.95		FRAS1_MOUSE (1-4008): 0: 2730: 84.84
+	Hs
		1204604 FREM1_HUMAN (4-221): 7.87e-38: 141: 18.83		FREM2_HUMAN (1229-3238): 1.69e-107: 390: 18.67
+	Mm
		1228173 FREM1_MOUSE (31-221): 6.48e-35: 132: 17.95		FREM2_MOUSE (1292-3338): 3.97e-101: 369: 17.22
+	Hs
		568017 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		NOTC3_HUMAN (355-1145): 4.51e-55: 217: 12.17
+	Hs
		567836 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46
+	Hs
		1047786 PRG3_HUMAN (12-222): 1.53e-53: 173: 49.30		NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46
+	Hs
		446107 FCER2_HUMAN (5-220): 1.84e-50: 168: 20.08		NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46
+	Hs
		567893 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		CSPG4_HUMAN (1108-2104): 1.57e-39: 165: 17.83
+	Hs
		567801 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		PCSK6_HUMAN (314-564): 5.18e-18: 94.2: 20.90
+	Hs
		567979 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		CHRD_HUMAN (90-280): 6.31e-15: 84.3: 32.11
+	Hs
		567940 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		PCSK5_HUMAN (12-434): 3.79e-14: 82: 13.91
+	Hs
		567812 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		NOTC1_HUMAN (5-403): 2.95e-12: 75.8: 13.25
+	Hs
		1369117 PRG3_HUMAN (12-222): 1.53e-53: 173: 49.30		PCSK5_HUMAN (12-434): 3.79e-14: 82: 13.91
+	Hs
		567989 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		CELR2_HUMAN (4-196): 8.58e-10: 67.8: 12.09
+	Hs
		567999 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		CELR1_HUMAN (540-695): 5.26e-09: 65.1: 12.14