Interactor 1: PMS1 (P14242)
DNA mismatch repair protein PMS1 (Postmeiotic segregation protein 1)
Gene: PMS1
Interactor 2: MLH1 (P38920)
DNA mismatch repair protein MLH1 (MutL protein homolog 1) (Post meiotic segregation protein 2)
Gene: MLH1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.993 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9545323, 23435383, 10570173, 11805826, 20080788, 8858149, 8066446, 9234704, 11901110, 10938116, 18206974, 16227575, 9368761, 11237696, 16429126, 28051769, 31351878, 34390347, 19015241, 24204293 and 9 others
more... |
| Identification Methods | biochemical, x-ray crystallography, two hybrid, tandem affinity purification, ion exchange chromatography, anti tag coimmunoprecipitation, coimmunoprecipitation, pull down, comigration in non denaturing gel electrophoresis, affinity chromatography technology and 1 others
more... |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_mis_repair~HATPase_c_3, HATPase_c_3~HATPase_c_3, Mlh1_C~MutL_C |
| Common GO terms | GO:0000710 - meiotic mismatch repair GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006298 - mismatch repair and 4 others more... |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
