HitPredict

Interactor 1: MLH1 (P40692)
DNA mismatch repair protein Mlh1 (MutL protein homolog 1)
Gene: MLH1

Interactor 2: MLH1 (P40692)
DNA mismatch repair protein Mlh1 (MutL protein homolog 1)
Gene: MLH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_mis_repair~HATPase_c_3, HATPase_c_3~HATPase_c_3, Mlh1_C~Mlh1_C
Common GO terms GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000712 - resolution of meiotic recombination intermediates
GO:0000795 - synaptonemal complex
GO:0001673 - male germ cell nucleus
GO:0003682 - chromatin binding
and 30 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 756
Hs

1 756
+ Hs
+ Sc
+ Hs
+ Hs
+ Dm
+ Sc
+ Ce
+ Sc
+ Sc
+ Dm
+ Ec
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025