Interactor 1: MLH1 (P38920)
DNA mismatch repair protein MLH1 (MutL protein homolog 1) (Post meiotic segregation protein 2)
Gene: MLH1
Interactor 2: MLH2 (Q07980)
DNA mismatch repair protein MLH2 (MutL protein homolog 2)
Gene: MLH2
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.969 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10570173, 16554755, 16429126, 33303966, 28051769, 31351878, 36942481, 24811092 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, biochemical, anti bait coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_mis_repair~HATPase_c_3, HATPase_c_3~HATPase_c_3 |
| Common GO terms | GO:0000710 - meiotic mismatch repair GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006298 - mismatch repair GO:0007131 - reciprocal meiotic recombination and 5 others more... |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
