HitPredict

Interactor 1: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Interactor 2: RD23A (P54725)
UV excision repair protein RAD23 homolog A (HR23A) (hHR23A)
Gene: RAD23A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19013454
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 439 Hs			1 363
+	Hs
		872133 PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60		RD23A_HUMAN (1-363): 4.01e-119: 350: 100.00
+	Rn
		906973 PRS4_RAT (32-433): 5.45e-136: 399: 43.60		RD23B_RAT (3-363): 6.38e-109: 326: 52.05
+	Rn
		1117332 PRS6A_RAT (1-439): 1.39e-135: 398: 99.32		RD23B_RAT (3-363): 6.38e-109: 326: 52.05
+	Hs
		872134 PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39		RD23A_HUMAN (1-363): 4.01e-119: 350: 100.00
+	Hs
		572907 PRS6A_HUMAN (1-439): 1.23e-136: 401: 100.00		RD23B_HUMAN (3-363): 1.37e-106: 320: 54.03
+	Rn
		1104198 Q32PW9_RAT (44-432): 5.05e-135: 394: 39.33		RD23B_RAT (3-363): 6.38e-109: 326: 52.05
+	Hs
		872248 PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60		RD23B_HUMAN (3-363): 1.37e-106: 320: 54.03
+	Hs
		872249 PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39		RD23B_HUMAN (3-363): 1.37e-106: 320: 54.03
+	Dm
		1359291 Q9V405_DROME (6-438): 4.77e-130: 383: 37.64		Q9V3W9_DROME (3-362): 9.91e-87: 269: 38.43
+	Dm
		820508 PRS4_DROME (5-433): 2.8e-136: 400: 42.49		Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90
+	Hs
		573110 PRS6A_HUMAN (1-439): 1.23e-136: 401: 100.00		UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47
+	Hs
		906946 PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60		UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47
+	Hs
		573100 PRS6A_HUMAN (1-439): 1.23e-136: 401: 100.00		UBQL2_HUMAN (2-312): 1.85e-45: 166: 16.08
+	Hs
		573087 PRS6A_HUMAN (1-439): 1.23e-136: 401: 100.00		UBQL4_HUMAN (3-312): 3.05e-45: 165: 15.57
+	Dm
		1181036 Q7KMQ0_DROME (21-433): 4.42e-126: 374: 36.87		Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90
+	Hs
		906941 PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60		UBQL2_HUMAN (2-312): 1.85e-45: 166: 16.08
+	Hs
		906929 PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60		UBQL4_HUMAN (3-312): 3.05e-45: 165: 15.57
+	Hs
		906808 PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60		RL40_HUMAN (3-129): 1.37e-38: 136: 22.84
+	Hs
		572921 PRS6A_HUMAN (1-439): 1.23e-136: 401: 100.00		RS27A_HUMAN (3-93): 2.9e-16: 77.1: 27.47
+	Hs
		906982 PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39		RS27A_HUMAN (3-93): 2.9e-16: 77.1: 27.47