HitPredict

Interactor 1: INSRR (P14616)
Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]
Gene: INSRR

Interactor 2: LRC49 (Q8IUZ0)
Leucine-rich repeat-containing protein 49 (Centriolar satellite-associated tubulin polyglutamylase complex regulator 2) (Tubulin polyglutamylase complex subunit 4) (PGs4)
Gene: LRRC49

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1297 Hs			1 686
+	Hs
		465517 IGF1R_HUMAN (9-1265): 0: 1177: 55.66		SCRIB_HUMAN (4-255): 5.8e-34: 141: 18.51
+	Hs
		465696 IGF1R_HUMAN (9-1265): 0: 1177: 55.66		NISCH_HUMAN (95-193): 8.34e-11: 67.8: 26.21
+	Hs
		710638 EPHA3_HUMAN (453-1267): 0: 607: 20.82		LRC49_HUMAN (1-686): 7.59e-108: 343: 100.00
+	Hs
		710350 EPHA2_HUMAN (455-1289): 0: 561: 21.88		LRC49_HUMAN (1-686): 7.59e-108: 343: 100.00
+	At
		87908 Y5182_ARATH (509-1286): 0: 572: 14.93		BAME1_ARATH (4-413): 1.21e-46: 180: 14.58
+	At
		87681 Y1756_ARATH (495-1274): 0: 564: 15.82		BAME1_ARATH (4-413): 1.21e-46: 180: 14.58
+	At
		88575 MEE39_ARATH (510-1287): 0: 562: 15.40		BAME1_ARATH (4-413): 1.21e-46: 180: 14.58
+	Hs
		1122235 EPHA7_HUMAN (454-1280): 0: 596: 20.31		SCRIB_HUMAN (4-255): 5.8e-34: 141: 18.51
+	Hs
		710831 EPHB2_HUMAN (455-1264): 0: 592: 19.82		SCRIB_HUMAN (4-255): 5.8e-34: 141: 18.51
+	Hs
		710238 EPHA2_HUMAN (455-1289): 0: 561: 21.88		SCRIB_HUMAN (4-255): 5.8e-34: 141: 18.51
+	Hs
		932158 EPHA4_HUMAN (455-1279): 0: 613: 20.70		NISCH_HUMAN (95-193): 8.34e-11: 67.8: 26.21
+	Hs
		710671 EPHA3_HUMAN (453-1267): 0: 607: 20.82		NISCH_HUMAN (95-193): 8.34e-11: 67.8: 26.21
+	Hs
		1147469 EPHA7_HUMAN (454-1280): 0: 596: 20.31		NISCH_HUMAN (95-193): 8.34e-11: 67.8: 26.21
+	At
		87903 Y5182_ARATH (509-1286): 0: 572: 14.93		RGI3_ARATH (282-612): 1.72e-17: 89: 7.26
+	Hs
		710920 EPHB2_HUMAN (455-1264): 0: 592: 19.82		NISCH_HUMAN (95-193): 8.34e-11: 67.8: 26.21
+	At
		87905 Y5182_ARATH (509-1286): 0: 572: 14.93		Y4361_ARATH (420-622): 1.58e-16: 85.9: 10.65
+	At
		87677 Y1756_ARATH (495-1274): 0: 564: 15.82		RGI3_ARATH (282-612): 1.72e-17: 89: 7.26
+	Hs
		931918 EPHA5_HUMAN (454-1279): 0: 585: 20.29		NISCH_HUMAN (95-193): 8.34e-11: 67.8: 26.21
+	At
		87711 Y1756_ARATH (495-1274): 0: 564: 15.82		Y1571_ARATH (353-610): 4.14e-16: 84.8: 9.89
+	At
		87930 Y5182_ARATH (509-1286): 0: 572: 14.93		CLV1_ARATH (2-92): 8.04e-12: 70.9: 11.70