HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28977666, 30890647
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 1912
+	Hs
		891769 ACTB_HUMAN (4-377): 0: 599: 94.12		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		891731 ACTB_HUMAN (4-377): 0: 599: 94.12		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		929837 ACTG_HUMAN (4-377): 0: 599: 94.39		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		932125 ACTC_HUMAN (1-377): 0: 599: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		229358 ACTC_HUMAN (1-377): 0: 599: 100.00		SMCA5_HUMAN (578-1624): 0: 791: 26.01
+	Zm
		13638 A0A1D6FW13_MAIZE (1-377): 0: 594: 88.06		A0A1D6MT91_MAIZE (576-1632): 0: 764: 26.97