HitPredict

Interactor 1: CSK2B (P67870)
Casein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a)
Gene: CSNK2B

Interactor 2: KS6B2 (Q9UBS0)
Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta)
Gene: RPS6KB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	33961781, 21988832
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	CK_II_beta~Pkinase
Common GO terms	GO:0004674 - protein serine/threonine kinase activity GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 482
+	Hs
		616695 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		KS6B1_HUMAN (1-476): 3.36e-173: 499: 68.58
+	Hs
		850634 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		KS6A3_HUMAN (5-380): 2.45e-105: 331: 26.85
+	Hs
		931650 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		KS6A1_HUMAN (5-380): 2.15e-105: 331: 25.19
+	Hs
		931649 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		KS6A2_HUMAN (5-380): 5.48e-104: 328: 26.46
+	Hs
		270398 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		KS6A5_HUMAN (2-325): 6.86e-97: 311: 23.32
+	Dm
		437155 CSK2B_DROME (1-215): 1.94e-134: 378: 88.37		Q9VR61_DROME (18-403): 5.76e-91: 297: 24.44
+	Hs
		272858 CSK2B_HUMAN (1-215): 2.27e-138: 387: 100.00		KS6A4_HUMAN (39-450): 2.95e-78: 261: 24.07