HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	30737378, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 488
+	Hs
		826803 TCPG_HUMAN (5-550): 0: 593: 33.03		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		573251 TCPA_HUMAN (1-556): 0: 630: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		826651 TCPG_HUMAN (5-550): 0: 593: 33.03		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038670 TCPH_HUMAN (1-545): 0: 566: 34.84		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177188 TCPA_HUMAN (1-556): 0: 630: 100.00		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		177233 TCPG_HUMAN (5-550): 0: 593: 33.03		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		177367 TCPH_HUMAN (1-545): 0: 566: 34.84		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Sc
		519912 TCPA_YEAST (4-542): 0: 558: 62.57		RPD3_YEAST (5-422): 0: 577: 60.95
+	Sc
		693017 TCPG_YEAST (1-538): 0: 552: 29.20		RPD3_YEAST (5-422): 0: 577: 60.95
+	Sp
		140519 TCPG_SCHPO (1-539): 0: 573: 30.44		PHD1_SCHPO (7-411): 0: 519: 52.56
+	Sp
		140556 TCPA_SCHPO (2-542): 0: 564: 65.87		PHD1_SCHPO (7-411): 0: 519: 52.56
+	Sp
		140638 TCPH_SCHPO (2-551): 0: 555: 36.32		PHD1_SCHPO (7-411): 0: 519: 52.56
+	Sc
		519976 TCPA_YEAST (4-542): 0: 558: 62.57		HOS2_YEAST (11-430): 5.02e-174: 498: 47.18
+	Sc
		760777 TCPG_YEAST (1-538): 0: 552: 29.20		HOS2_YEAST (11-430): 5.02e-174: 498: 47.18
+	Mm
		945965 TCPE_MOUSE (4-532): 0: 623: 32.03		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Mm
		516943 TCPA_MOUSE (1-556): 0: 622: 96.40		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Mm
		945920 TCPH_MOUSE (1-551): 0: 577: 35.18		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Hs
		573514 TCPA_HUMAN (1-556): 0: 630: 100.00		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		826927 TCPG_HUMAN (5-550): 0: 593: 33.03		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		1306720 TCPH_HUMAN (1-545): 0: 566: 34.84		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04