Protein: NFYA
Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA)

Gene: NFYA
Organism: Homo sapiens
Interactions: 85
UniProt ID: P23511

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

617728

NFYB
Nuclear transcription factor Y subunit beta

10

11

Small-scale

0.978

High

617751

NFYC
Nuclear transcription factor Y subunit gamma

9

20

Small-scale

0.756

High

617742

CSK21
Casein kinase II subunit alpha

4

6

High-throughput

0.705

High

386108

P53
Cellular tumor antigen p53

4

1

Small-scale

0.698

High

434948

SP1
Transcription factor Sp1

4

1

Small-scale

0.697

High

617746

EP300
Histone acetyltransferase p300

4

1

Small-scale

0.680

High

617738

TF2AA
Transcription initiation factor IIA subunit 1

4

0

High-throughput

0.668

High

617759

POGZ
Pogo transposable element with ZNF domain

3

0

High-throughput

0.646

High

617727

CDK2
Cyclin-dependent kinase 2

2

3

Small-scale

0.634

High

617781

TES
Testin

2

1

High-throughput

0.628

High

617769

ZC3HA
Zinc finger CCCH domain-containing protein 10

3

0

High-throughput

0.626

High

617782

ZHX1
Zinc fingers and homeoboxes protein 1

2

1

Small-scale

0.622

High

617764

APBP2
Amyloid protein-binding protein 2

2

0

High-throughput

0.613

High

617741

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

1

High-throughput

0.611

High

540784

PO2F1
POU domain, class 2, transcription factor 1

2

1

High-throughput

0.606

High

617748

4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2

2

0

High-throughput

0.602

High

617755

UAP1
UDP-N-acetylhexosamine pyrophosphorylase

2

0

High-throughput

0.602

High

617772

CHM4A
Charged multivesicular body protein 4a

2

0

High-throughput

0.602

High

617774

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

2

0

High-throughput

0.602

High

401430

JUN
Transcription factor Jun

2

3

Small-scale

0.584

High

617739

ATX1
Ataxin-1

2

0

High-throughput

0.580

High

617752

VEZF1
Vascular endothelial zinc finger 1

2

0

High-throughput

0.580

High

617757

QRIC1
Transcriptional regulator QRICH1

2

0

High-throughput

0.580

High

617761

BANP
Protein BANP

2

0

High-throughput

0.580

High

617767

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

0

High-throughput

0.580

High

617773

UBL5
Ubiquitin-like protein 5

2

0

High-throughput

0.580

High

617749

HDAC1
Histone deacetylase 1

2

0

Small-scale

0.559

High

617766

KAT2B
Histone acetyltransferase KAT2B

2

0

Small-scale

0.547

High

617747

SRBP2
Sterol regulatory element-binding protein 2

1

2

High-throughput

0.541

High

617750

PWP1
Periodic tryptophan protein 1 homolog

1

1

High-throughput

0.541

High

617734

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

Small-scale

0.537

High

617763

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

Small-scale

0.537

High

127187

IPO5
Importin-5

1

2

High-throughput

0.536

High

556781

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

High-throughput

0.536

High

233740

NDK8
Putative nucleoside diphosphate kinase

2

0

High-throughput

0.528

High

515555

SRF
Serum response factor

1

1

Small-scale

0.527

High

617729

MPIP1
M-phase inducer phosphatase 1

1

0

High-throughput

0.518

High

617771

PAPOG
Poly(A) polymerase gamma

1

0

High-throughput

0.518

High

617745

SRSF1
Serine/arginine-rich splicing factor 1

1

0

Small-scale

0.513

High

617776

PHAX
Phosphorylated adapter RNA export protein

1

0

High-throughput

0.513

High

617779

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.513

High

572537

SPI1
Transcription factor PU.1

1

1

Small-scale

0.501

High

590123

CCNA2
Cyclin-A2

1

1

Small-scale

0.501

High

590562

PO3F2
POU domain, class 3, transcription factor 2

1

2

Small-scale

0.501

High

617737

TAF6
Transcription initiation factor TFIID subunit 6

1

1

Small-scale

0.501

High

617756

TAF12
Transcription initiation factor TFIID subunit 12

1

1

Small-scale

0.501

High

579314

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

4

Small-scale

0.481

High

617770

ATF6B
Cyclic AMP-dependent transcription factor ATF-6 beta

1

4

Small-scale

0.481

High

394136

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

564802

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

Small-scale

0.480

High

617731

ELF1
ETS-related transcription factor Elf-1

1

0

Small-scale

0.480

High

617754

TAF11
Transcription initiation factor TFIID subunit 11

1

0

Small-scale

0.480

High

538469

CCNB1
G2/mitotic-specific cyclin-B1

1

1

Small-scale

0.479

High

547703

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

5

Small-scale

0.479

High

571793

XBP1
X-box-binding protein 1

1

3

Small-scale

0.479

High

617733

BRCA1
Breast cancer type 1 susceptibility protein

1

1

Small-scale

0.479

High

617736

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

Small-scale

0.479

High

617765

CBP
CREB-binding protein

1

1

Small-scale

0.479

High

617775

P63
Tumor protein 63

1

1

Small-scale

0.479

High

617785

ZHX2
Zinc fingers and homeoboxes protein 2

1

1

Small-scale

0.479

High

617732

TGFR2
TGF-beta receptor type-2

1

1

Small-scale

0.470

High

265601

E2F6
Transcription factor E2F6

1

0

Small-scale

0.460

High

211499

ACTN4
Alpha-actinin-4

1

0

Small-scale

0.458

High

276142

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

0

Small-scale

0.458

High

368994

ESR1
Estrogen receptor

1

0

Small-scale

0.458

High

572283

LEG3
Galectin-3

1

0

Small-scale

0.458

High

575272

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

617744

TOP2B
DNA topoisomerase 2-beta

1

0

Small-scale

0.458

High

617778

TLR9
Toll-like receptor 9

1

0

Small-scale

0.458

High

617780

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

617777

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

617783

LC7L2
Putative RNA-binding protein Luc7-like 2

4

0

High-throughput

0.364

High

617743

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

3

0

High-throughput

0.347

High

617762

IRGQ
Immunity-related GTPase family Q protein

3

0

High-throughput

0.347

High

617784

TCAF1
TRPM8 channel-associated factor 1

3

0

High-throughput

0.341

High

617730

ILEU
Leukocyte elastase inhibitor

2

0

High-throughput

0.328

High

617735

MAOX
NADP-dependent malic enzyme

2

0

High-throughput

0.318

High

617753

LASP1
LIM and SH3 domain protein 1

2

0

High-throughput

0.318

High

617758

BROX
BRO1 domain-containing protein BROX

1

0

High-throughput

0.279

Low

617760

MINK1
Misshapen-like kinase 1

1

0

High-throughput

0.279

Low

617768

PLPP
Chronophin

1

0

High-throughput

0.279

Low

335241

DYR
Dihydrofolate reductase

1

0

Small-scale

0.249

Low

421299

HYEP
Epoxide hydrolase 1

1

0

Small-scale

0.249

Low

517903

COBA1

1

0

Small-scale

0.249

Low

617740

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024