HitPredict

Interactor 1: NELFE (P18615)
Negative elongation factor E (NELF-E) (RNA-binding protein RD)
Gene: NELFE

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 245
+	Hs
		577744 NELFE_HUMAN (1-380): 2.83e-83: 260: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		577728 NELFE_HUMAN (1-380): 2.83e-83: 260: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		577732 NELFE_HUMAN (1-380): 2.83e-83: 260: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		577743 NELFE_HUMAN (1-380): 2.83e-83: 260: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		577750 NELFE_HUMAN (1-380): 2.83e-83: 260: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49