HitPredict

Interactor 1: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Interactor 2: ROA0 (Q13151)
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)
Gene: HNRNPA0

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19738201, 22623428
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006954 - inflammatory response GO:0032496 - response to lipopolysaccharide
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 739 Hs			1 305
+	Hs
		581428 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		581824 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		MSI2H_HUMAN (5-303): 2.55e-56: 186: 32.11
+	Hs
		581713 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67
+	Hs
		516354 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		453137 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		581561 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		581825 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		DAZP1_HUMAN (2-96): 1.3e-19: 90: 31.58
+	Hs
		581722 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		161960 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91
+	Hs
		609973 TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		1031405 TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24		PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67
+	Hs
		516609 TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		1104165 TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24		RA1L2_HUMAN (85-183): 1.21e-20: 92: 34.34
+	Hs
		162098 TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91