HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: AP2M1 (P84092)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	32357304
Identification Methods	cross-linking study, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 752 Rn			1 435
+	Rn
		94205 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		AP2M1_RAT (1-435): 1.03e-178: 507: 100.00
+	Mm
		498008 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		AP2M1_MOUSE (1-435): 1.03e-178: 507: 100.00
+	Hs
		497422 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		497548 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		654028 MAP4_HUMAN (9-727): 1.28e-34: 144: 19.84		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		497844 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AP3M1_HUMAN (1-434): 1.4e-123: 366: 24.66
+	Hs
		496626 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AP3M2_HUMAN (1-434): 2.92e-119: 355: 24.89
+	Hs
		203244 SYNJ1_HUMAN (395-731): 7.71e-09: 61.6: 13.27		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Dm
		248311 Q9VLS7_DROME (3-541): 3.66e-12: 72.4: 11.77		O62530_DROME (1-435): 7.78e-171: 487: 86.56