HitPredict

Interactor 1: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15659383
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 455 Hs			1 193
+	Hs
		584368 TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436154 TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		154335 TR10B_HUMAN (31-445): 1.86e-78: 252: 19.81		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		154338 TR10B_HUMAN (31-445): 1.86e-78: 252: 19.81		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		154295 TR10B_HUMAN (31-445): 1.86e-78: 252: 19.81		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		154343 TR10B_HUMAN (31-445): 1.86e-78: 252: 19.81		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		154333 TR10B_HUMAN (31-445): 1.86e-78: 252: 19.81		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		154300 TR10B_HUMAN (31-445): 1.86e-78: 252: 19.81		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		154332 TR10B_HUMAN (31-445): 1.86e-78: 252: 19.81		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		154336 TR10B_HUMAN (31-445): 1.86e-78: 252: 19.81		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		121467 TR10A_HUMAN (51-445): 8.24e-66: 220: 17.57		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		121470 TR10A_HUMAN (51-445): 8.24e-66: 220: 17.57		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		121431 TR10A_HUMAN (51-445): 8.24e-66: 220: 17.57		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		121472 TR10A_HUMAN (51-445): 8.24e-66: 220: 17.57		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		121466 TR10A_HUMAN (51-445): 8.24e-66: 220: 17.57		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		121436 TR10A_HUMAN (51-445): 8.24e-66: 220: 17.57		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		121464 TR10A_HUMAN (51-445): 8.24e-66: 220: 17.57		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		121469 TR10A_HUMAN (51-445): 8.24e-66: 220: 17.57		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		738654 TNR3_HUMAN (11-328): 5.78e-63: 211: 24.85		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		120192 TR10A_HUMAN (51-445): 8.24e-66: 220: 17.57		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98