HitPredict

Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: ANKH1 (Q8IWZ3)
Ankyrin repeat and KH domain-containing protein 1 (HIV-1 Vpr-binding ankyrin repeat protein) (Multiple ankyrin repeats single KH domain) (hMASK)
Gene: ANKHD1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	25609649
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank~Ank_4, Ank_2~Ank_2, Ank_2~Ank_4, Ank_2~RHD_dimer
Common GO terms	GO:0005737 - cytoplasm GO:0045087 - innate immune response
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 968 Hs			1 2542
+	Mm
		103591 ANK3_MOUSE (381-967): 1e-99: 346: 14.24		ANK3_MOUSE (1-391): 3.31e-87: 321: 19.95
+	Hs
		167036 ANR50_HUMAN (360-930): 1.1e-108: 369: 13.96		ANR28_HUMAN (1159-1401): 6.69e-59: 225: 28.81
+	Hs
		166913 ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37		ANR28_HUMAN (1159-1401): 6.69e-59: 225: 28.81
+	Hs
		167028 ANR28_HUMAN (650-967): 1.41e-49: 192: 14.82		ANFY1_HUMAN (778-1387): 4.2e-70: 261: 16.69
+	Hs
		1237559 ANR44_HUMAN (654-967): 1.34e-46: 183: 14.06		ANFY1_HUMAN (778-1387): 4.2e-70: 261: 16.69
+	Hs
		166971 ANR28_HUMAN (650-967): 1.41e-49: 192: 14.82		ANR52_HUMAN (5-393): 1.49e-66: 249: 16.83
+	Hs
		166849 ANR28_HUMAN (650-967): 1.41e-49: 192: 14.82		ANR28_HUMAN (1159-1401): 6.69e-59: 225: 28.81
+	Mm
		103608 ANK3_MOUSE (381-967): 1e-99: 346: 14.24		ANK2_MOUSE (1489-2530): 3.97e-09: 65: 8.43
+	Hs
		167014 ANR28_HUMAN (650-967): 1.41e-49: 192: 14.82		TNKS2_HUMAN (1194-1530): 3.72e-45: 182: 23.06
+	Hs
		166869 ANR28_HUMAN (650-967): 1.41e-49: 192: 14.82		TNKS1_HUMAN (1194-1429): 2.78e-41: 170: 27.41
+	Hs
		166882 BCL3_HUMAN (366-702): 1.13e-31: 131: 19.71		ANR28_HUMAN (1159-1401): 6.69e-59: 225: 28.81
+	Hs
		166969 ANR28_HUMAN (650-967): 1.41e-49: 192: 14.82		ANR44_HUMAN (30-237): 3.12e-32: 140: 12.45
+	Hs
		883487 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		ANK2_HUMAN (1449-2492): 2.93e-12: 75: 10.78
+	Hs
		883496 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		ANK3_HUMAN (2106-2514): 8.65e-09: 63.8: 10.85
+	Hs
		166919 ANR28_HUMAN (650-967): 1.41e-49: 192: 14.82		ANK3_HUMAN (2106-2514): 8.65e-09: 63.8: 10.85