HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20347428
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 2048
+	Hs
		588828 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		ERC6L_HUMAN (1-1232): 6.67e-116: 402: 11.22
+	Hs
		587979 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		SMCA1_HUMAN (4-1033): 2.63e-114: 392: 13.28
+	Hs
		590048 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		DICER_HUMAN (78-615): 2.47e-108: 387: 17.99
+	Hs
		243526 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		SMCA5_HUMAN (4-1010): 2.26e-108: 375: 12.19
+	Hs
		589750 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		CHD8_HUMAN (42-1069): 1.84e-99: 360: 12.12
+	Hs
		588713 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		CHD4_HUMAN (41-1138): 3.05e-96: 349: 12.34
+	Ce
		759563 Q95Y97_CAEEL (1-262): 1.01e-78: 241: 20.42		DCR1_CAEEL (91-1462): 3.55e-130: 455: 13.86
+	Hs
		1096709 RFA4_HUMAN (1-268): 6.9e-96: 283: 45.56		ERC6L_HUMAN (1-1232): 6.67e-116: 402: 11.22
+	Hs
		589319 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		XPF_HUMAN (1746-2032): 1.39e-85: 304: 19.42
+	Sc
		688751 RFA2_YEAST (4-264): 9.52e-71: 220: 25.61		MPH1_YEAST (60-729): 7.33e-88: 313: 28.01
+	Hs
		587869 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		DDX5_HUMAN (13-421): 4.42e-20: 98.9: 14.09
+	Hs
		141312 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		DDX3X_HUMAN (19-341): 3.88e-19: 96.2: 15.70
+	Hs
		589787 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		DDX21_HUMAN (473-672): 2.67e-15: 84.1: 20.48
+	Hs
		589972 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		DDX20_HUMAN (70-447): 2.46e-14: 81.2: 11.11
+	Hs
		608574 RFA4_HUMAN (1-268): 6.9e-96: 283: 45.56		DDX5_HUMAN (13-421): 4.42e-20: 98.9: 14.09
+	Hs
		1096825 RFA4_HUMAN (1-268): 6.9e-96: 283: 45.56		DDX21_HUMAN (473-672): 2.67e-15: 84.1: 20.48