HitPredict

Interactor 1: TIMP2 (P16035)
Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2)
Gene: TIMP2

Interactor 2: K1C17 (Q04695)
Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)
Gene: KRT17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	39238192
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 220 Hs			1 432
+	Hs
		476262 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		K1C16_HUMAN (80-410): 1.71e-159: 460: 79.28
+	Hs
		385048 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		K1C14_HUMAN (82-430): 3.38e-151: 438: 82.40
+	Hs
		566094 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		K1C10_HUMAN (79-389): 1.16e-123: 372: 69.75
+	Hs
		407248 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		K2C6B_HUMAN (50-414): 7.91e-71: 235: 23.43
+	Hs
		566327 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		K2C5_HUMAN (50-398): 9.61e-71: 235: 25.07
+	Hs
		385234 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		K2C6A_HUMAN (50-414): 1.1e-69: 232: 23.71
+	Hs
		370015 TIMP1_HUMAN (10-203): 5.84e-86: 255: 42.29		KRT35_HUMAN (2-395): 2.09e-79: 254: 51.72
+	Hs
		590903 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		KRT81_HUMAN (7-430): 5.66e-11: 66.4: 11.98
+	Hs
		590949 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		KRT82_HUMAN (135-423): 3.11e-09: 61: 15.16