HitPredict

Interactor 1: LRP2 (A2ARV4)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Interactor 2: ARH (Q8C142)
Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog)
Gene: Ldlrap1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	23836931
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4660 Mm			1 308
+	Rn
		92834 LRP2_RAT (1-4660): 0: 3826: 93.88		ARH_RAT (1-308): 4.38e-95: 285: 95.78
+	Hs
		1022618 LRP2_HUMAN (1-4660): 0: 3732: 76.64		ARH_HUMAN (1-308): 5.57e-100: 297: 89.32
+	Mm
		59780 LRP2_MOUSE (1-4660): 0: 3817: 100.00		DAB1_MOUSE (43-302): 6.02e-50: 176: 19.27
+	Rn
		313033 LRP2_RAT (1-4660): 0: 3826: 93.88		DAB2_RAT (8-307): 2.35e-43: 160: 15.14
+	Mm
		59781 LRP2_MOUSE (1-4660): 0: 3817: 100.00		DAB2_MOUSE (8-307): 4.98e-44: 162: 15.46
+	Hs
		1022627 LRP2_HUMAN (1-4660): 0: 3732: 76.64		ANS1B_HUMAN (13-230): 1.28e-50: 181: 22.07
+	Hs
		269758 LRP2_HUMAN (1-4660): 0: 3732: 76.64		CAPON_HUMAN (34-300): 7.71e-52: 179: 22.92
+	Hs
		286357 LRP2_HUMAN (1-4660): 0: 3732: 76.64		DAB1_HUMAN (43-302): 3.83e-51: 179: 20.51
+	Mm
		59790 LRP2_MOUSE (1-4660): 0: 3817: 100.00		JIP1_MOUSE (47-169): 9.82e-16: 79.5: 21.21
+	Hs
		1022147 LRP2_HUMAN (1-4660): 0: 3732: 76.64		DAB2_HUMAN (8-307): 1.37e-42: 157: 15.46
+	Hs
		1022669 LRP2_HUMAN (1-4660): 0: 3732: 76.64		JIP1_HUMAN (47-169): 1.45e-15: 79.1: 21.21
+	Hs
		376509 LDLR_HUMAN (2603-2890): 7.51e-16: 87.2: 19.24		ARH_HUMAN (1-308): 5.57e-100: 297: 89.32
+	Mm
		1021148 VLDLR_MOUSE (183-468): 4.28e-19: 98: 22.95		DAB1_MOUSE (43-302): 6.02e-50: 176: 19.27
+	Hs
		286337 LDLR_HUMAN (2603-2890): 7.51e-16: 87.2: 19.24		DAB1_HUMAN (43-302): 3.83e-51: 179: 20.51
+	Hs
		286356 VLDLR_HUMAN (920-1171): 9.67e-14: 80.3: 18.58		DAB1_HUMAN (43-302): 3.83e-51: 179: 20.51
+	Mm
		778027 LDLR_MOUSE (926-1243): 2.14e-14: 82.6: 19.12		DAB1_MOUSE (43-302): 6.02e-50: 176: 19.27
+	Mm
		73127 B1AXJ3_MOUSE (3435-3650): 4.79e-10: 68.3: 16.37		DAB1_MOUSE (43-302): 6.02e-50: 176: 19.27
+	Hs
		376496 LDLR_HUMAN (2603-2890): 7.51e-16: 87.2: 19.24		DAB2_HUMAN (8-307): 1.37e-42: 157: 15.46
+	Mm
		1354131 LRP4_MOUSE (180-443): 2.91e-18: 95.7: 22.22		JIP1_MOUSE (47-169): 9.82e-16: 79.5: 21.21
+	Mm
		73136 B1AXJ3_MOUSE (3435-3650): 4.79e-10: 68.3: 16.37		JIP1_MOUSE (47-169): 9.82e-16: 79.5: 21.21