Protein: JIP1
C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain 1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1)

Gene: JIP1, MAPK8IP1
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q9UQF2

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0005078 - MAP-kinase scaffold activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

423472

A4
Amyloid-beta precursor protein

7

20

Small-scale

0.969

High

1103743

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

3

11

Small-scale

0.879

High

214070

M3K7
Mitogen-activated protein kinase kinase kinase 7

3

15

Small-scale

0.847

High

1159145

M3K11
Mitogen-activated protein kinase kinase kinase 11

2

9

Small-scale

0.834

High

411120

ERBB2
Receptor tyrosine-protein kinase erbB-2

3

20

High-throughput

0.828

High

1030714

ANK2
Ankyrin-2

2

3

High-throughput

0.811

High

1091477

ANK3
Ankyrin-3

2

3

High-throughput

0.811

High

1460937

FEM1B
Protein fem-1 homolog B

2

4

High-throughput

0.811

High

1462741

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

2

14

Small-scale

0.754

High

853757

MK08
Mitogen-activated protein kinase 8

10

9

Small-scale

0.754

High

853870

MK09
Mitogen-activated protein kinase 9

5

9

Small-scale

0.726

High

1038583

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

18

Small-scale

0.724

High

1087713

M3K12
Mitogen-activated protein kinase kinase kinase 12

1

20

Small-scale

0.724

High

1402537

NEB2
Neurabin-2

1

16

High-throughput

0.691

High

162058

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

3

10

Small-scale

0.678

High

728488

AKT1
RAC-alpha serine/threonine-protein kinase

3

9

Small-scale

0.670

High

364045

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

725125

HXC8
Homeobox protein Hox-C8

2

9

High-throughput

0.628

High

1129943

TTLL4
Tubulin monoglutamylase TTLL4

2

1

High-throughput

0.628

High

1393267

SENP5
Sentrin-specific protease 5

2

1

High-throughput

0.628

High

1462571

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

2

8

High-throughput

0.628

High

212039

M3K13
Mitogen-activated protein kinase kinase kinase 13

1

15

Small-scale

0.618

High

1092518

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

8

Small-scale

0.618

High

1352644

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

17

Small-scale

0.618

High

1022669

LRP2
Low-density lipoprotein receptor-related protein 2

2

20

Small-scale

0.609

High

1060938

LRP1
Prolow-density lipoprotein receptor-related protein 1

2

20

Small-scale

0.609

High

1275986

SETX
Probable helicase senataxin

2

0

High-throughput

0.602

High

1120590

LRP8
Low-density lipoprotein receptor-related protein 8

2

20

Small-scale

0.594

High

440792

FYN
Tyrosine-protein kinase Fyn

1

18

High-throughput

0.590

High

1060591

KLC1
Kinesin light chain 1

2

6

Small-scale

0.584

High

1417911

DUS16
Dual specificity protein phosphatase 16

1

2

Small-scale

0.578

High

316331

RECQ5
ATP-dependent DNA helicase Q5

1

3

High-throughput

0.541

High

1361852

RSPH1
Radial spoke head 1 homolog

1

1

High-throughput

0.541

High

861843

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

High-throughput

0.536

High

1108755

TBB3
Tubulin beta-3 chain

1

10

High-throughput

0.536

High

1121562

KEAP1
Kelch-like ECH-associated protein 1

1

6

High-throughput

0.536

High

1192010

TBB8
Tubulin beta-8 chain

1

10

High-throughput

0.536

High

1294523

VRK2
Serine/threonine-protein kinase VRK2

1

2

Small-scale

0.536

High

1365622

MY18A
Unconventional myosin-XVIIIa

1

4

High-throughput

0.536

High

171116

VP26C
Vacuolar protein sorting-associated protein 26C

1

0

High-throughput

0.518

High

530603

TAU
Microtubule-associated protein tau

1

4

Small-scale

0.515

High

1125950

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

0

High-throughput

0.513

High

424045

ITB3
Integrin beta-3

1

11

Small-scale

0.501

High

155973

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.479

High

858733

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

8

Small-scale

0.479

High

956805

RAB10
Ras-related protein Rab-10

1

4

Small-scale

0.479

High

1040094

PAX2
Paired box protein Pax-2

1

1

Small-scale

0.479

High

430522

JUN
Transcription factor Jun

1

0

Small-scale

0.458

High

947316

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High


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Last updated: 11Aug2025