HitPredict

Interactor 1: DAB1 (P97318)
Disabled homolog 1 (mDab1)
Gene: DAB1

Interactor 2: VLDLR (P98156)
Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R)
Gene: VLDLR

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.642

Property	Details
Experiments	10380922, 15249135, 10827173
Identification Methods	pull down, affinity chromatography technology, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0021517 - ventral spinal cord development GO:0038026 - reelin-mediated signaling pathway GO:0045202 - synapse GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Mm			1 873
+	Hs
		286356 DAB1_HUMAN (1-588): 1.28e-78: 261: 91.50		VLDLR_HUMAN (19-873): 0: 711: 96.02
+	Mm
		778027 DAB1_MOUSE (1-588): 2.09e-86: 281: 100.00		LDLR_MOUSE (4-224): 5.3e-24: 110: 24.05
+	Mm
		73127 DAB1_MOUSE (1-588): 2.09e-86: 281: 100.00		B1AXJ3_MOUSE (2-192): 5.09e-22: 104: 20.66
+	Hs
		286368 DAB1_HUMAN (1-588): 1.28e-78: 261: 91.50		LRP8_HUMAN (9-269): 4.95e-27: 120: 29.71
+	Mm
		1021160 DAB1_MOUSE (1-588): 2.09e-86: 281: 100.00		LRP8_MOUSE (230-431): 1.9e-17: 89.5: 25.98
+	Hs
		286337 DAB1_HUMAN (1-588): 1.28e-78: 261: 91.50		LDLR_HUMAN (236-455): 9.62e-20: 96.8: 25.42
+	Mm
		59780 DAB1_MOUSE (1-588): 2.09e-86: 281: 100.00		LRP2_MOUSE (221-487): 4.2e-12: 72.5: 17.65
+	Mm
		1021159 DAB1_MOUSE (1-588): 2.09e-86: 281: 100.00		LRP1_MOUSE (3-160): 7.55e-10: 65.2: 14.79
+	Hs
		286357 DAB1_HUMAN (1-588): 1.28e-78: 261: 91.50		LRP2_HUMAN (2-149): 1.34e-11: 71: 18.35
+	Hs
		286364 DAB1_HUMAN (1-588): 1.28e-78: 261: 91.50		LRP1_HUMAN (4-232): 2.87e-09: 63.3: 16.09
+	Hs
		376509 ARH_HUMAN (11-271): 2.48e-48: 172: 18.35		LDLR_HUMAN (236-455): 9.62e-20: 96.8: 25.42
+	Hs
		1060927 GULP1_HUMAN (17-327): 1.69e-59: 202: 19.69		LRP1_HUMAN (4-232): 2.87e-09: 63.3: 16.09
+	Hs
		376496 DAB2_HUMAN (8-584): 2.29e-39: 155: 25.47		LDLR_HUMAN (236-455): 9.62e-20: 96.8: 25.42
+	Hs
		1022618 ARH_HUMAN (11-271): 2.48e-48: 172: 18.35		LRP2_HUMAN (2-149): 1.34e-11: 71: 18.35
+	Hs
		1022627 ANS1B_HUMAN (8-229): 3.5e-44: 171: 16.81		LRP2_HUMAN (2-149): 1.34e-11: 71: 18.35
+	Hs
		287552 DAB2_HUMAN (8-584): 2.29e-39: 155: 25.47		LRP6_HUMAN (237-392): 1.14e-15: 84.1: 29.70
+	Mm
		59785 ARH_MOUSE (8-271): 5.78e-45: 163: 16.67		LRP2_MOUSE (221-487): 4.2e-12: 72.5: 17.65
+	Hs
		1060889 ANS1B_HUMAN (8-229): 3.5e-44: 171: 16.81		LRP1_HUMAN (4-232): 2.87e-09: 63.3: 16.09
+	Mm
		59781 DAB2_MOUSE (8-587): 2.67e-40: 158: 25.71		LRP2_MOUSE (221-487): 4.2e-12: 72.5: 17.65
+	Rn
		313033 DAB2_RAT (8-587): 8.2e-41: 160: 25.34		LRP2_RAT (2-140): 5.65e-09: 62.5: 18.54