HitPredict

Interactor 1: VDAC1 (P21796)
Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM)
Gene: VDAC1

Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.726

The method score is based on:

Property Details
Experiments 20080789, 15637055, 12767928, 10737788, 10365962
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0019901 - protein kinase binding
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 283
Hs

1 233
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024