Protein: HDA2
HDA1 complex subunit 2 (Histone deacetylase complex 1 subunit 2)

Gene: HDA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 126
UniProt ID: Q06629

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

866878

HDA1
Histone deacetylase HDA1

6

0

Small-scale

0.904

High

988444

HDA3
HDA1 complex subunit 3

5

0

Small-scale

0.887

High

639292

MSH2
DNA mismatch repair protein MSH2

3

0

High-throughput

0.637

High

708061

NUF2
Kinetochore protein NUF2

3

0

High-throughput

0.617

High

979636

SPC24
Kinetochore protein SPC24

3

0

High-throughput

0.617

High

988455

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.589

High

597140

ACE2
Metallothionein expression activator

2

0

High-throughput

0.570

High

778476

MAD1
Spindle assembly checkpoint component MAD1

2

0

High-throughput

0.570

High

812437

NNF1
Kinetochore-associated protein NNF1

2

0

High-throughput

0.570

High

495056

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

512861

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.513

High

636757

CDC48
Cell division control protein 48

1

0

High-throughput

0.493

High

710580

UBX1
UBX domain-containing protein 1

1

0

High-throughput

0.493

High

521158

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.486

High

988456

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.486

High

605698

KIN3
Serine/threonine-protein kinase KIN3

1

1

High-throughput

0.481

High

772345

ATAD2
ATPase histone chaperone YTA7

1

1

High-throughput

0.481

High

811566

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

1

High-throughput

0.481

High

861377

AP18B
Clathrin coat assembly protein AP180B

1

1

High-throughput

0.481

High

979214

VPS20
Vacuolar protein sorting-associated protein 20

1

1

High-throughput

0.481

High

615070

KC12
Casein kinase I homolog 2

1

0

High-throughput

0.480

High

693749

IME2
Meiosis induction protein kinase IME2/SME1

1

0

High-throughput

0.480

High

410030

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.460

High

515018

RNA1
Ran GTPase-activating protein 1

1

0

High-throughput

0.460

High

587889

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.460

High

599933

RE107
Recombination protein 107

1

0

High-throughput

0.460

High

603339

SNF2
Transcription regulatory protein SNF2

1

0

High-throughput

0.460

High

679808

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.460

High

689641

MET4
Transcriptional activator of sulfur metabolism MET4

1

0

High-throughput

0.460

High

701935

SWE1
Mitosis inhibitor protein kinase SWE1

1

0

High-throughput

0.460

High

702725

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

703748

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

705960

SPC29
Spindle pole component 29

1

0

High-throughput

0.460

High

706065

NIP80
Protein NIP100

1

0

High-throughput

0.460

High

710824

CASP
Protein CASP

1

0

High-throughput

0.460

High

732518

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.460

High

747725

SP381
Pre-mRNA-splicing factor SPP381

1

0

High-throughput

0.460

High

752816

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.460

High

757083

SKN7
Transcription factor SKN7

1

0

High-throughput

0.460

High

766828

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

767553

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.460

High

771522

NACB2
Nascent polypeptide-associated complex subunit beta-2

1

0

High-throughput

0.460

High

772521

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.460

High

772548

SEC9
Protein transport protein SEC9

1

0

High-throughput

0.460

High

784918

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.460

High

792459

GZF3
Protein GZF3

1

0

High-throughput

0.460

High

810371

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.460

High

810620

YJ41B
Transposon Ty4-J Gag-Pol polyprotein

1

0

High-throughput

0.460

High

811079

SNX4
Sorting nexin-4

1

0

High-throughput

0.460

High

811093

VPS53
Vacuolar protein sorting-associated protein 53

1

0

High-throughput

0.460

High

812222

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.460

High

820699

TBCA
Tubulin-specific chaperone A

1

0

High-throughput

0.460

High

859137

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.460

High

860983

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.460

High

866321

AF9
Protein AF-9 homolog

1

0

High-throughput

0.460

High

953690

CTR9
RNA polymerase-associated protein CTR9

1

0

High-throughput

0.460

High

972073

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.460

High

976402

NHP10
Non-histone protein 10

1

0

High-throughput

0.460

High

987941

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

988044

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.460

High

988458

SGO1
Shugoshin

1

0

High-throughput

0.460

High

988459

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.460

High

988460

MDN1
Midasin

1

0

High-throughput

0.460

High

988461

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.460

High

988462

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.460

High

988463

GYP5
GTPase-activating protein GYP5

1

0

High-throughput

0.460

High

988466

SKS1
Serine/threonine-protein kinase SKS1

1

0

High-throughput

0.460

High

663417

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

694259

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

762585

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

766994

CHZ1
Histone H2A.Z-specific chaperone CHZ1

1

0

High-throughput

0.458

High

492548

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

681022

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

731149

LHS1
Heat shock protein 70 homolog LHS1

1

2

High-throughput

0.439

High

732422

STB6
Protein STB6

1

1

High-throughput

0.439

High

763991

HPH2
Protein HPH2

1

1

High-throughput

0.439

High

764896

SNF7
Vacuolar-sorting protein SNF7

1

1

High-throughput

0.439

High

805296

STB2
Protein STB2

1

1

High-throughput

0.439

High

988467

HPH1
Protein HPH1

1

1

High-throughput

0.439

High

969213

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.438

High

366949

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

705697

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

959879

NUM1
Nuclear migration protein NUM1

2

0

High-throughput

0.310

High

805040

FAR3
Factor arrest protein 3

2

0

Small-scale

0.300

High

635473

ARE1
Sterol O-acyltransferase 1

1

0

High-throughput

0.251

Low

688941

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

696988

YEF3
Uncharacterized protein YEL043W

1

0

High-throughput

0.251

Low

704808

SLA2
Protein SLA2

1

0

High-throughput

0.251

Low

711153

SEG2
Eisosome protein SEG2

1

0

High-throughput

0.251

Low

731363

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.251

Low

731979

RT22
Ribosome assembly protein RSM22, mitochondrial

1

0

High-throughput

0.251

Low

734084

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.251

Low

734320

JNM1
Nuclear migration protein JNM1

1

0

High-throughput

0.251

Low

743410

AP2A
AP-2 complex subunit alpha

1

0

High-throughput

0.251

Low

746791

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

747600

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.251

Low

753585

ETP1
RING finger protein ETP1

1

0

High-throughput

0.251

Low

755162

LAM4
Membrane-anchored lipid-binding protein LAM4

1

0

High-throughput

0.251

Low

756582

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.251

Low

759274

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.251

Low

763728

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

784666

BNI1
Protein BNI1

1

0

High-throughput

0.251

Low

797235

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

810737

NET1
Nucleolar protein NET1

1

0

High-throughput

0.251

Low

810985

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

811231

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.251

Low

812566

SGM1
Protein SGM1

1

0

High-throughput

0.251

Low

816946

CCM1
Mitochondrial 15S rRNA processing factor CCM1

1

0

High-throughput

0.251

Low

859677

SP105
Spindle pole body component SPC105

1

0

High-throughput

0.251

Low

860691

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

861119

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.251

Low

935912

DID2
Vacuolar protein-sorting-associated protein 46

1

0

High-throughput

0.251

Low

935999

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.251

Low

974460

SVL3
Styryl dye vacuolar localization protein 3

1

0

High-throughput

0.251

Low

978092

SPC19
DASH complex subunit SPC19

1

0

High-throughput

0.251

Low

978607

SHE9
Sensitive to high expression protein 9, mitochondrial

1

0

High-throughput

0.251

Low

982685

IVY1
Protein IVY1

1

0

High-throughput

0.251

Low

984785

ENT2
Epsin-2

1

0

High-throughput

0.251

Low

986348

FMP27
Protein FMP27, mitochondrial

1

0

High-throughput

0.251

Low

986646

SEC10
Exocyst complex component SEC10

1

0

High-throughput

0.251

Low

986880

MMR1
Mitochondrial MYO2 receptor-related protein 1

1

0

High-throughput

0.251

Low

988457

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.251

Low

988464

BBP1
Spindle pole component BBP1

1

0

High-throughput

0.251

Low

988465

ERP3
Protein ERP3

1

0

High-throughput

0.251

Low

485837

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024