HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 821 Hs			1 592
+	Hs
		507869 FGFR1_HUMAN (1-820): 0: 772: 71.17		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		607885 FGFR4_HUMAN (22-810): 0: 684: 55.86		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		161008 FGFR1_HUMAN (1-820): 0: 772: 71.17		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		654090 EPHA3_HUMAN (18-778): 3.24e-168: 514: 18.30		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654101 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654370 NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654272 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		434139 RET_HUMAN (228-816): 2.74e-144: 455: 34.26		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		384315 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		161071 NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161054 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161002 RET_HUMAN (228-816): 2.74e-144: 455: 34.26		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		160995 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		654124 FLT3_HUMAN (342-800): 5.44e-85: 293: 36.15		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		161031 FLT3_HUMAN (342-800): 5.44e-85: 293: 36.15		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		653493 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Hs
		654121 VGFR3_HUMAN (42-385): 5.85e-18: 91.4: 17.62		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		384313 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Hs
		161030 VGFR3_HUMAN (42-385): 5.85e-18: 91.4: 17.62		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		653500 VGFR3_HUMAN (42-385): 5.85e-18: 91.4: 17.62		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33