HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 821 Hs			1 582
+	Hs
		508038 FGFR1_HUMAN (1-820): 0: 772: 71.17		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		609325 FGFR3_HUMAN (10-821): 0: 731: 65.69		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		607994 FGFR4_HUMAN (22-810): 0: 684: 55.86		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		609513 FGFR3_HUMAN (10-821): 0: 731: 65.69		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		384944 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		674526 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11
+	Hs
		674414 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		516373 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		384090 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		384775 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		384175 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		385048 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		674545 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		972371 TIE2_HUMAN (7-763): 1.63e-155: 485: 22.83		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		385269 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		385606 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		385028 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		384903 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		738280 FLT3_HUMAN (342-800): 5.44e-85: 293: 36.15		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		572691 VGFR1_HUMAN (5-134): 1.03e-11: 70.9: 16.42		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84