HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 4128
+	Hs
		665578 EPHB2_HUMAN (1-788): 0: 624: 19.15		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		944263 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		738194 FLT3_HUMAN (11-791): 1.67e-162: 499: 23.74		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		384640 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		944192 TIE2_HUMAN (478-783): 3.47e-72: 258: 44.77		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		729637 VGFR2_HUMAN (5-342): 3.81e-17: 88.6: 16.58		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		729260 VGFR3_HUMAN (7-245): 8.53e-15: 81: 18.22		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		572617 VGFR1_HUMAN (40-357): 6.77e-13: 74.8: 13.25		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		601494 FGFR2_HUMAN (1-114): 9.04e-12: 70.9: 17.56		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		738299 FLT3_HUMAN (11-791): 1.67e-162: 499: 23.74		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Hs
		787493 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		MTOR_HUMAN (2776-4127): 0: 695: 15.99
+	Hs
		872435 EPHA5_HUMAN (1-777): 0: 622: 20.18		ATM_HUMAN (3218-4128): 1.84e-158: 557: 19.42