Interactor 1: XPA (P23025)
DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein)
Gene: XPA

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.55 0.727

The method score is based on:

Property Details
Experiments 28854355, 7700386, 33961781, 7565690, 12641457, 8972858, 19446504, 7876167, 7665601, 9535929, 20304803, 12527904
Identification Methods affinity chromatography technology, pull down, two hybrid, coimmunoprecipitation, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
GO:0006284 - base-excision repair
and 2 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024