HitPredict

Interactor 1: PTPRA (P18433)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)
Gene: PTPRA

Interactor 2: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27880917, 32062451
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 694
+	Hs
		659022 PTPRG_HUMAN (14-798): 0: 784: 29.12		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00
+	Hs
		1090055 PTPRJ_HUMAN (516-797): 4.65e-118: 389: 38.87		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00
+	Hs
		658823 PTPRB_HUMAN (443-796): 9.06e-116: 388: 31.11		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00
+	Hs
		1106479 PTPRO_HUMAN (509-789): 7.31e-114: 375: 34.51		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00
+	Hs
		711205 PTN6_HUMAN (504-796): 2.35e-112: 356: 32.47		GAB2_HUMAN (3-691): 1.85e-144: 438: 38.73
+	Hs
		471743 PTPRC_HUMAN (207-516): 1.17e-77: 275: 29.12		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00
+	Hs
		848996 PTN9_HUMAN (265-500): 1.67e-47: 180: 39.92		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00
+	Hs
		711194 PTN6_HUMAN (504-796): 2.35e-112: 356: 32.47		PKHA2_HUMAN (2-194): 4.15e-35: 140: 20.77