HitPredict

Interactor 1: KS6B1 (P23443)
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)
Gene: RPS6KB1

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 525 Hs			1 616
+	Hs
		650467 AKT2_HUMAN (3-416): 5.02e-151: 442: 38.66		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		650466 AKT1_HUMAN (34-418): 1.81e-150: 440: 39.90		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		566294 KPCA_HUMAN (4-419): 2.83e-142: 426: 35.55		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		568552 KAPCA_HUMAN (80-397): 6.73e-143: 417: 36.79		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		270375 KS6A5_HUMAN (4-349): 1.07e-103: 330: 24.73		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		650723 KS6A3_HUMAN (3-405): 3.09e-104: 330: 24.04		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651283 KS6A1_HUMAN (6-405): 2.39e-104: 330: 23.79		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		652560 KS6A6_HUMAN (3-412): 3.24e-101: 322: 22.75		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Dm
		1097973 Q94533_DROME (19-493): 8.92e-156: 454: 58.11		RFA1_DROME (1-614): 0: 619: 41.00