HitPredict

Interactor 1: CADH2 (P19022)
Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)
Gene: CDH2

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 18302981, 34079125, 33961781, 35271311, 39358380, 36950384, 25143387, 14625392, 12604612, 37071682, 16707106, 24614104, 11835406, 12077367, 17098867, 18948590, 17679699, 17510365, 21357690, 17057644
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~CADH_Y-type_LIR
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0005912 - adherens junction
GO:0005916 - fascia adherens
and 18 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 906
Hs

1 781
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Last updated: 11Aug2025