HitPredict

Interactor 1: ASCL1 (P19359)
Achaete-scute homolog 1
Gene: ASCL1

Interactor 2: HES5 (Q03062)
Transcription factor HES-5 (Hairy and enhancer of split 5)
Gene: HES5

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17006542
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003682 - chromatin binding
GO:0003690 - double-stranded DNA binding
and 13 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 233
Rn

1 166
+ Mm
+ Mm
+ Mm
+ Dm
+ Dm
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Mm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025