HitPredict

Interactor 1: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Interactor 2: RIPK3 (Q9Y572)
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)
Gene: RIPK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	10339433
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 455 Hs			1 518
+	Hs
		622608 TNR1A_HUMAN (1-455): 2.08e-147: 429: 100.00		RIPK1_HUMAN (21-288): 1.19e-33: 137: 33.90
+	Hs
		214383 TNR1A_HUMAN (1-455): 2.08e-147: 429: 100.00		RIPK2_HUMAN (14-291): 6.45e-33: 133: 32.32
+	Mm
		669415 TNR1A_MOUSE (1-445): 8.4e-128: 379: 64.37		RIPK1_MOUSE (15-276): 1e-35: 142: 34.39
+	Hs
		163297 TR10B_HUMAN (39-445): 5.55e-78: 251: 20.43		RIPK1_HUMAN (21-288): 1.19e-33: 137: 33.90
+	Hs
		1109641 TNR25_HUMAN (39-442): 8.1e-78: 249: 27.36		RIPK1_HUMAN (21-288): 1.19e-33: 137: 33.90
+	Hs
		630271 TNR1B_HUMAN (7-278): 8.97e-47: 169: 20.00		RIPK1_HUMAN (21-288): 1.19e-33: 137: 33.90
+	Hs
		675020 TNR6_HUMAN (1-167): 1.19e-46: 165: 23.21		RIPK1_HUMAN (21-288): 1.19e-33: 137: 33.90
+	Hs
		214387 TNR5_HUMAN (38-315): 1.41e-47: 166: 19.29		RIPK2_HUMAN (14-291): 6.45e-33: 133: 32.32
+	Mm
		866566 TNR4_MOUSE (52-252): 1.15e-31: 123: 17.91		RIPK1_MOUSE (15-276): 1e-35: 142: 34.39
+	Hs
		214375 TNR16_HUMAN (40-303): 2.38e-28: 118: 15.48		RIPK2_HUMAN (14-291): 6.45e-33: 133: 32.32