Interactor 1: IL4RA (P24394)
Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124) [Cleaved into: Soluble interleukin-4 receptor subunit alpha (Soluble IL-4 receptor subunit alpha) (Soluble IL-4R-alpha) (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)]
Gene: IL4R

Interactor 2: IL4RA (P24394)
Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124) [Cleaved into: Soluble interleukin-4 receptor subunit alpha (Soluble IL-4 receptor subunit alpha) (Soluble IL-4R-alpha) (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)]
Gene: IL4R

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 21058338
Identification Methods fluorescence correlation spectroscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL4Ra_N~IL4Ra_N
Common GO terms GO:0002532 - production of molecular mediator involved in inflammatory response
GO:0002639 - positive regulation of immunoglobulin production
GO:0004896 - cytokine receptor activity
GO:0004913 - interleukin-4 receptor activity
GO:0005576 - extracellular region
and 20 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 825
Hs

1 825
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Last updated: 15 Jul 2024