HitPredict

Interactor 1: EF1B (P24534)
Elongation factor 1-beta (EF-1-beta)
Gene: EEF1B2

Interactor 2: EF1A2 (Q05639)
Elongation factor 1-alpha 2 (EF-1-alpha-2) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1)
Gene: EEF1A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.867

Property	Details
Experiments	28514442, 17353931, 33961781
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF1_GNE~GTP_EFTU, EF1_GNE~GTP_EFTU_D2
Common GO terms	GO:0003746 - translation elongation factor activity GO:0005737 - cytoplasm GO:0005853 - eukaryotic translation elongation factor 1 complex GO:0006414 - translational elongation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 225 Hs			1 463
+	Hs
		623101 EF1B_HUMAN (1-225): 2.59e-105: 304: 100.00		EF1A1_HUMAN (1-462): 0: 558: 92.42
+	Hs
		669343 EF1D_HUMAN (52-225): 9.96e-73: 224: 64.41		EF1A2_HUMAN (1-463): 0: 560: 100.00
+	Hs
		669331 EF1D_HUMAN (52-225): 9.96e-73: 224: 64.41		EF1A1_HUMAN (1-462): 0: 558: 92.42
+	Sc
		367850 EF1B_YEAST (1-225): 1.1e-61: 193: 46.02		EF1A_YEAST (1-443): 0: 523: 80.14
+	Dm
		399196 EF1D_DROME (79-225): 1.32e-52: 171: 58.50		EF1A2_DROME (1-452): 0: 534: 84.07